| 128 | Richy Jing (CAR) def. Ashul Satav (GCM) 6-3, 6-1 |
| 128 | Victor Pimenta (CARTH) def. Andrew Dumbauld (UWW) 6-2, 6-4 |
| 128 | Colin Chapman (UWEC) def. Jumpei Kasai (COEM) 6-3, 6-4 |
| 128 | Jordan Oaks (UWW) def. Dane Patten (CSS) 6-3, 6-3 |
| 128 | Joao Benvenutti (LUTM) def. Thomas Kampmeier (LOR) 6-2, 6-2 |
| 128 | Nick Scott (CENM) def. Ryan Fonseca (UWEC) 7-5, 6-4 |
| 128 | Ricky Portilla (LUTM) def. Marcos Borobia Arias (BLCMT) 7-6, 6-1 |
| 128 | Alec Sargent (MAC) def. Ryan Will (SJU) 6-1, 6-4 |
| 128 | Joao Benvenutti (LUTM) def. Renan Revite (CUW) 6-3, 6-4 |
| 128 | Payton Adkisson (UWW) def. Trent Devore (CCM) 6-1, 6-2 |
| 128 | Jonas Abeleda (CSS) def. Jacob Young (GCM) 6-4, 6-4 |
| 128 | Luca Okina (CARTH) def. Ali Derbani (GACM) 7-5, 6-3 |
| 128 | Bogdan Vizoli (STO) def. Liam Lynch (MAC) 1-6, 7-5, 10-7 |
| 128 | Louk Rijsdijk (LUTM) def. Evan Huemoeller (SMU) 6-3, 6-2 |
| 128 | Cade Davis (WARMT) def. Joe Chong (MSOE) 6-1, 7-6 |
| 128 | Diego Silva (CARTH) def. Marjan Veldic (STO) 6-1, 6-2 |
| 128 | Lev van Hemert (LUTM) def. Elijah Swanstrom (WARMT) 6-2, 6-2 |
| 128 | Eamon Gerrard-Stace (CSS) def. Igor Guetten Chaves (UWSM) 6-3, 1-6, 10-8 |
| 128 | Alexander Hadler (CCM) def. Ian Aadland (SJU) 6-4, 6-2 |
| 128 | Chase Lindwall (UWW) def. Grant Idoux (COEM) 6-3, 6-1 |
| 128 | Cooper Kline (CAR) def. Jordan Doi (MAC) 6-2, 6-4 |
| 128 | Pablo Rincon (UWEC) def. Albert Bostoen (GCM) 7-5, 6-3 |
| 128 | Cooper Ferruzzi (CARTH) def. Geoffrey Youngs (GACM) 7-5, 7-5 |
| 128 | Sam Wolden (SJU) def. Ivan Burt-Smith (COEM) 6-1, 6-3 |
| 128 | Deuce Daniel (GCM) def. Heitor Damaso (BLCMT) 6-1, 6-0 |
| 128 | Sydney Vinnedge (UWW) def. Brady Horstmann (UWL) 6-2, 7-6 |
| 128 | Andres Saavedra (MSOE) def. Abhay Chhabra (LUTM) 6-3, 6-1 |
| 128 | Stewart Morrell (UNW) def. Gage Becker (LOR) 6-1, 7-6 |
| 128 | Cyriac Cayuela (CARTH) def. AJ Wilkins (CENM) 6-0, 6-1 |
| 128 | Andrew LaBelle (CU) def. Jacob Zacharias (UWSM) 6-1, 6-1 |
| 128 | Landon Sather (CUW) def. Ethan Wurtzel (UWEC) 3-6, 6-4, 10-5 |
| 64 | Luke Westholder (LUTM) def. Richy Jing (CAR) 6-4, 6-2 |
| 64 | Tyler Haddorff (GACM) def. Victor Pimenta (CARTH) 6-3, 7-6 |
| 64 | Adrian Gomez (CU) def. Colin Chapman (UWEC) 6-4, 6-2 |
| 64 | Luke Fridinger (GACM) def. Jordan Oaks (UWW) 6-2, 6-3 |
| 64 | Rafael Costa (GACM) def. Ren Kurachi (UWSM) 6-2, 6-0 |
| 64 | Lucas Willett (GCM) def. Nick Scott (CENM) 6-3, 6-1 |
| 64 | Giovanni Vitali (UWW) def. Ricky Portilla (LUTM) 6-0, 6-1 |
| 64 | Elions Braind (CARTH) def. Alec Sargent (MAC) 6-2, 6-1 |
| 64 | Josh Christensen (GACM) def. Joao Benvenutti (LUTM) 6-4, 6-2 |
| 64 | Myles Krzewinski (CARTH) def. Payton Adkisson (UWW) 7-5, 6-1 |
| 64 | Demetri Bush (UWEC) def. Jonas Abeleda (CSS) 6-2, 7-5 |
| 64 | Luke VanDonslear (UWW) def. Luca Okina (CARTH) 6-2, 6-3 |
| 64 | Bogdan Vizoli (STO) def. Graham Peterson (COEM) 6-2, 1-6, 10-7 |
| 64 | Dominik Knutson (GACM) def. Louk Rijsdijk (LUTM) 6-2, 6-2 |
| 64 | Sam Rudenberg (GCM) def. Cade Davis (WARMT) 6-0, 6-2 |
| 64 | Will Ulrich (UWW) def. Diego Silva (CARTH) 6-2, 6-4 |
| 64 | Wilder Cooke (GCM) def. Lev van Hemert (LUTM) 7-6, 6-2 |
| 64 | Gavin Hutter (BU) def. Eamon Gerrard-Stace (CSS) 6-1, 6-1 |
| 64 | Gage Gohl (GACM) def. Alexander Hadler (CCM) 6-2, 6-1 |
| 64 | Felipe Biscaro (LUTM) def. Chase Lindwall (UWW) 6-4, 6-2 |
| 64 | Caleb Fridinger (GACM) def. Cooper Kline (CAR) 6-0, 6-2 |
| 64 | Daniel Ezcurra (CU) def. Pablo Rincon (UWEC) 6-1, 7-6 |
| 64 | Reuben Giorgio (UWW) def. Cooper Ferruzzi (CARTH) 3-6, 4-1, retired |
| 64 | Drew VanFossen (UWW) def. Ivan Burt-Smith (COEM) 6-3, 6-1 |
| 64 | Jack Bergmeyer (GACM) def. Deuce Daniel (GCM) 6-1, 4-6, 10-7 |
| 64 | Taona Mhwandagara (GACM) def. Sydney Vinnedge (UWW) 6-1, 6-2 |
| 64 | Francisco Silveira (CARTH) def. Andres Saavedra (MSOE) 7-6, 6-4 |
| 64 | Max Loen (LUTM) def. Stewart Morrell (UNW) 6-7, 6-4, 10-6 |
| 64 | Tyler Nelson (UWW) def. Cyriac Cayuela (CARTH) 6-1, 6-4 |
| 64 | Yuv Kataria (CAR) def. Andrew LaBelle (CU) 6-3, 6-3 |
| 64 | Marco Siviero (GACM) def. Landon Sather (CUW) 6-3, 4-6, 10-4 |
| 32 | Tyler Haddorff (GACM) def. Luke Westholder (LUTM) 6-3, 7-6 |
| 32 | Luke Fridinger (GACM) def. Adrian Gomez (CU) 6-3, 5-7, 10-7 |
| 32 | Rafael Costa (GACM) def. Lucas Willett (GCM) 6-4, 7-5 |
| 32 | Elions Braind (CARTH) def. Giovanni Vitali (UWW) 6-4, 3-6, 11-9 |
| 32 | Josh Christensen (GACM) def. Steven Benoy (UWSPM) 6-1, 6-1 |
| 32 | Myles Krzewinski (CARTH) def. Demetri Bush (UWEC) 7-5, 6-4 |
| 32 | Luke VanDonslear (UWW) def. Bogdan Vizoli (STO) 6-2, 6-4 |
| 32 | Dominik Knutson (GACM) def. Sam Rudenberg (GCM) 6-2, 6-1 |
| 32 | Wilder Cooke (GCM) def. Will Ulrich (UWW) 6-1, 7-6 |
| 32 | Gage Gohl (GACM) def. Gavin Hutter (BU) 6-1, 6-2 |
| 32 | Caleb Fridinger (GACM) def. Felipe Biscaro (LUTM) 6-3, 6-4 |
| 32 | Reuben Giorgio (UWW) def. Daniel Ezcurra (CU) 6-4, 6-2 |
| 32 | Jack Bergmeyer (GACM) def. Drew VanFossen (UWW) 6-3, 1-6, 10-2 |
| 32 | Francisco Silveira (CARTH) def. Taona Mhwandagara (GACM) 5-7, 6-4, 10-5 |
| 32 | Tyler Nelson (UWW) def. Max Loen (LUTM) 6-7, 6-4, 10-7 |
| 32 | Marco Siviero (GACM) def. Yuv Kataria (CAR) 6-0, 6-1 |
| 16 | Luke Fridinger (GACM) def. Tyler Haddorff (GACM) 6-3, 6-3 |
| 16 | Rafael Costa (GACM) def. Elions Braind (CARTH) 6-3, 5-7, 10-7 |
| 16 | Josh Christensen (GACM) def. Myles Krzewinski (CARTH) 6-3, 7-5 |
| 16 | Luke VanDonslear (UWW) def. Dominik Knutson (GACM) 7-6, 6-2 |
| 16 | Gage Gohl (GACM) def. Wilder Cooke (GCM) 6-4, 7-5 |
| 16 | Caleb Fridinger (GACM) def. Reuben Giorgio (UWW) 6-3, 3-6, 10-3 |
| 16 | Jack Bergmeyer (GACM) def. Francisco Silveira (CARTH) 4-6, 6-3, 10-7 |
| 16 | Marco Siviero (GACM) def. Tyler Nelson (UWW) 7-6, 4-5, retired |
| QF | Rafael Costa (GACM) def. Luke Fridinger (GACM) 6-3, 7-6 |
| QF | Luke VanDonslear (UWW) def. Josh Christensen (GACM) 6-4, 6-4 |
| QF | Gage Gohl (GACM) def. Caleb Fridinger (GACM) 6-1, 6-2 |
| QF | Marco Siviero (GACM) def. Jack Bergmeyer (GACM) 4-6, 7-5, 13-11 |
| SF | Luke VanDonslear (UWW) def. Rafael Costa (GACM) 6-4, 6-1 |
| SF | Gage Gohl (GACM) def. Marco Siviero (GACM) 6-4, 6-4 |
| F | Gage Gohl (GACM) def. Luke VanDonslear (UWW) 6-3, 7-5 |
